Description

n-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-[(1R,2R)-2-(1-Piperidinyl)Cyclohexyl]-Thiourea is a high-purity, chiral thiourea derivative designed for advanced chemical synthesis and research. This compound is valued for its role as a sophisticated organocatalyst and a key chiral building block in the development of active pharmaceutical ingredients (APIs). It is essential for researchers and process chemists in pharmaceutical R&D, agrochemical development, and advanced material science, where precise stereochemistry and functional group manipulation are critical.

Application

• Organocatalyst in asymmetric synthesis for creating enantiomerically pure compounds.
• Chiral Intermediate in the multi-step synthesis of novel pharmaceutical candidates and agrochemicals.
• Ligand Precursor for the development of metal-complex catalysts used in fine chemical manufacturing.
• Research Chemical for studying hydrogen-bonding catalysis and anion recognition processes.
• Building Block for constructing complex molecules in medicinal chemistry and material science projects.

Basic Information

Product Name	n-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-[(1R,2R)-2-(1-Piperidinyl)Cyclohexyl]-Thiourea
CAS No.	1289514-24-4
Molecular Formula	C22H28F6N3S
Molecular Weight	496.54 g/mol
Synonyms	(1R,2R)-N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[2-(piperidin-1-yl)cyclohexyl]thiourea; (1R,2R)-1-[3-[3,5-Bis(trifluoromethyl)phenyl]thioureido]-2-piperidin-1-ylcyclohexane; TRISPHAT Thiourea Derivative; Chiral Bis(trifluoromethyl)phenyl Thiourea Catalyst; N-(3,5-Bis(trifluoromethyl)phenyl)-N'-((1R,2R)-2-(piperidin-1-yl)cyclohexyl)thiourea
EINECS	Contact for details

Quality Control

Our n-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-[(1R,2R)-2-(1-Piperidinyl)Cyclohexyl]-Thiourea is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing purity, enantiomeric excess, and identification data is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive compound from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.