Description

Potassium (4-Bromophenylsulfonamido)Methyltrifluoroborate is a high-purity organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling robust and selective cross-coupling reactions, particularly Suzuki-Miyaura couplings, due to its enhanced stability and reactivity profile compared to traditional boronic acids. This advanced reagent is essential for researchers and process chemists in pharmaceutical development, agrochemical synthesis, and materials science, where it facilitates the efficient construction of complex biaryl and heterobiaryl structures. The compound is supplied with CAS No. 1286686-29-0.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing complex drug candidates, especially those containing biphenyl or heterobiaryl motifs via palladium-catalyzed cross-coupling reactions.
• Agrochemical Research & Development: Used in the synthesis of novel active ingredients for crop protection, where the 4-bromophenyl moiety is a common structural feature.
• Materials Science & OLED Development: Serves as a precursor for creating organic electronic materials, including charge-transport layers and emissive compounds in organic light-emitting diodes (OLEDs).
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology & Probe Development: Useful for the site-specific modification of biomolecules or the creation of chemical probes for biological target identification.
• Academic & Process Chemistry Research: A valuable tool for method development and scaling up synthetic routes in both academic and industrial R&D settings.

Basic Information

Product Name	Potassium (4-Bromophenylsulfonamido)Methyltrifluoroborate
CAS No.	1286686-29-0
Molecular Formula	C7H7BBrF3KNO2S
Molecular Weight	349.01 g/mol
Synonyms	Potassium [(4-Bromophenyl)sulfonyl]aminomethyltrifluoroborate; Potassium N-[(4-Bromophenyl)sulfonyl]aminomethyltrifluoroborate; Potassium Trifluoro[(4-bromophenylsulfonyl)amino]methylborate; (4-Bromobenzenesulfonamido)methyltrifluoroborate Potassium Salt; Potassium (4-Bromobenzenesulfonamidomethyl)trifluoroborate; N-[(4-Bromophenyl)sulfonyl]-1-amino-1-trifluoroboratomethane Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium (4-Bromophenylsulfonamido)Methyltrifluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay (by 19F/11B NMR or HPLC), identity confirmation, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system supports traceability and regulatory compliance for advanced R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. For long-term storage, consider storing desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95%
Purity (NMR)	≥95%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.