Description

Potassium (2-Bromophenylsulfonamido)Methyltrifluoroborate is a specialized organotrifluoroborate salt, a valuable class of reagents in modern synthetic chemistry. This compound serves as a stable, air- and moisture-tolerant precursor for generating reactive boronic acid derivatives under mild conditions, enabling critical carbon-carbon bond-forming reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex organic molecules and advanced intermediates.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a key coupling partner for the introduction of the (2-bromophenylsulfonamido)methyl moiety into biaryl and heterobiaryl systems.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing sulfonamide pharmacophores.
• Agrochemical Compound Development: Employed in creating novel herbicides, fungicides, and insecticides that require specific aryl-sulfonamide structures.
• Material Science Research: Serves as a building block for synthesizing functional organic materials and ligands for catalysis.
• Process Chemistry & Scale-Up: Its stability makes it suitable for optimizing and scaling coupling reactions from laboratory to pilot plant scale.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in medicinal chemistry.

Basic Information

Product Name	Potassium (2-Bromophenylsulfonamido)Methyltrifluoroborate
CAS No.	1286686-28-9
Molecular Formula	C7H7BBrF3KNO2S
Molecular Weight	341.01 g/mol
Synonyms	Potassium [(2-Bromophenyl)sulfamoyl]methyltrifluoroborate; Potassium N-[(2-Bromophenyl)sulfonyl]aminomethyltrifluoroborate; (2-Bromobenzenesulfonamido)methyltrifluoroborate Potassium Salt; Potassium Trifluoro[(2-bromophenylsulfonylamino)methyl]borate; K-OrgBoron Reagent; Potassium Organotrifluoroborate Salt
EINECS	Contact for details

Quality Control

Our Potassium (2-Bromophenylsulfonamido)Methyltrifluoroborate is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B, ¹⁹F) for structural confirmation and HPLC for purity assessment. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain stability and purity. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
¹H NMR Purity	≥ 95%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.