Description

(R)-n-(Piperidin-3-Yl)-Tetrahydro-2H-Pyran-4-Carboxamide Hydrochloride is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is of significant value for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), particularly in neurological and psychiatric therapeutic areas. It is primarily utilized by research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs for novel therapeutic agents.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Employed as an analytical standard for quality control and method validation in API manufacturing.
• Biochemical Tool Compound: Utilized in preclinical research to investigate specific biological pathways and receptor interactions.

Basic Information

Product Name	(R)-n-(Piperidin-3-Yl)-Tetrahydro-2H-Pyran-4-Carboxamide Hydrochloride
CAS No.	1286208-60-3
Molecular Formula	C11H21ClN2O2
Molecular Weight	248.75 g/mol
Synonyms	(R)-N-(Piperidin-3-yl)oxane-4-carboxamide hydrochloride; Tetrahydro-2H-pyran-4-carboxamide, N-(3R)-3-piperidinyl-, hydrochloride (1:1); (R)-N-(Piperidin-3-yl)tetrahydro-2H-pyran-4-carboxamide HCl; (3R)-N-(Oxan-4-yl)piperidine-3-carboxamide hydrochloride; (R)-3-[(Tetrahydro-2H-pyran-4-carbonyl)amino]piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-n-(Piperidin-3-Yl)-Tetrahydro-2H-Pyran-4-Carboxamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and development. A detailed Certificate of Analysis (COA) providing identity, purity (HPLC), and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.