Description

3-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridazine is a high-value, functionalized pyridazine derivative featuring a pinacol boronate ester group, making it a critical building block in modern synthetic chemistry. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. It is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for creating biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and tool compounds for studying biological pathways and target engagement.
• Catalyst Ligand Synthesis: Utilized for constructing sophisticated ligand frameworks used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up campaigns in fine chemical production.

Basic Information

Product Name	3-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridazine
CAS No.	1283136-35-5
Molecular Formula	C₁₁H₁₇BN₂O₂
Molecular Weight	220.08 g/mol
Synonyms	3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridazine; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methylpyridazine; 3-Methyl-6-(pinacolatoboryl)pyridazine; 3-Methylpyridazine-6-boronic acid pinacol ester; 6-Borono-3-methylpyridazine pinacol ester; Pyridazine, 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 1283136-35-5
EINECS	Contact for details

Quality Control

Our 3-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent lot-to-lot performance critical for sensitive cross-coupling reactions. Certificates of Analysis (COA) with full analytical data are provided to guarantee compliance with your research and process specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle and store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity. Recommended storage temperature: 2-8°C (refrigerated) for prolonged shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.