Description

n-(2-Methoxyphenyl)-2-[3-(Morpholin-4-Yl)-6-Oxopyridazin-1(6H)-Yl]Acetamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a key building block for creating molecules with targeted therapeutic effects. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new drug candidates, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of new chemical entities.
• API Development: Integral in the process development and scale-up stages for new Active Pharmaceutical Ingredients, leveraging its morpholine and pyridazinone motifs.
• Biochemical Tool Compound: May be employed in vitro as a probe or inhibitor to study specific enzymatic or receptor-based biological mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or non-GMP conditions as required.

Basic Information

Product Name	n-(2-Methoxyphenyl)-2-[3-(Morpholin-4-Yl)-6-Oxopyridazin-1(6H)-Yl]Acetamide
CAS No.	1282099-07-3
Molecular Formula	C17H20N4O4
Molecular Weight	344.37 g/mol
Synonyms	2-(3-Morpholino-6-oxopyridazin-1(6H)-yl)-N-(2-methoxyphenyl)acetamide; N-(2-Methoxyphenyl)-2-(3-morpholino-6-oxo-1,6-dihydropyridazin-1-yl)acetamide; 1(6H)-Pyridazinone, 3-(4-morpholinyl)-1-[2-[(2-methoxyphenyl)amino]-2-oxoethyl]-; UNII-6J2H3F3C4F; Acetamide, N-(2-methoxyphenyl)-2-[3-(4-morpholinyl)-6-oxo-1(6H)-pyridazinyl]-; 1282099-07-3
EINECS	Contact for details

Quality Control

Our n-(2-Methoxyphenyl)-2-[3-(Morpholin-4-Yl)-6-Oxopyridazin-1(6H)-Yl]Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), related substances, and residual solvents. Our quality commitment supports development work from research to pre-clinical stages, with scalability under controlled conditions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.