Description

(2S,3R,4S,5S,6R)-2-(3-(4-((S)-Tetrahydrofuran-3-Yloxy)Benzyl)-4-Chlorophenyl)-Tetrahydro-6-(Hydroxymethyl)-2-Methoxy-2H-Pyran-3,4,5-Triol is a high-purity, complex organic intermediate of significant interest in advanced pharmaceutical research and development. This compound, with CAS number 1279691-36-9, is valued for its precise stereochemistry and functional groups, which make it a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of complex drug candidates, particularly in oncology and metabolic disease research.
• Process Chemistry & R&D: Used in route scouting, optimization studies, and scale-up activities for new chemical entities (NCEs).
• Reference Standard: Employed as an analytical standard for method development, validation, and quality control in API manufacturing.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to explore and modify biological activity.
• Custom Synthesis: Acts as a starting material or intermediate for contract research organizations (CROs) and CDMOs offering bespoke chemical services.

Basic Information

Product Name	(2S,3R,4S,5S,6R)-2-(3-(4-((S)-Tetrahydrofuran-3-Yloxy)Benzyl)-4-Chlorophenyl)-Tetrahydro-6-(Hydroxymethyl)-2-Methoxy-2H-Pyran-3,4,5-Triol
CAS No.	1279691-36-9
Molecular Formula	C24H29ClO8
Molecular Weight	480.94 g/mol
Synonyms	(2S,3R,4S,5S,6R)-2-[3-[4-[(3S)-Oxolan-3-yloxy]phenyl]methyl]-4-chlorophenyl]-6-(hydroxymethyl)-2-methoxyoxane-3,4,5-triol; CAS 1279691-36-9; (2S,3R,4S,5S,6R)-2-(3-(4-((S)-Tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol; Tetrahydro-6-(hydroxymethyl)-2-methoxy-2H-pyran-3,4,5-triol derivative; Chlorophenyl tetrahydrofuranoxy benzyl glucitol derivative.
EINECS	Contact for details

Quality Control

Our (2S,3R,4S,5S,6R)-2-(3-(4-((S)-Tetrahydrofuran-3-Yloxy)Benzyl)-4-Chlorophenyl)-Tetrahydro-6-(Hydroxymethyl)-2-Methoxy-2H-Pyran-3,4,5-Triol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, chiral analysis, and structural confirmation via NMR and MS, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.