Description

Potassium Methyltrifluoroborate is an organoboron reagent widely used as a stable, air- and moisture-tolerant source of the methyl anion in cross-coupling reactions. This compound matters because it offers superior handling characteristics and shelf-life compared to traditional, highly reactive organometallic reagents, enabling more efficient and scalable synthetic processes. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex organic molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key methylating agent for coupling with aryl or vinyl halides to form methyl-arenes or methyl-alkenes, crucial in pharmaceutical intermediate synthesis.
• Pharmaceutical Intermediate Manufacturing: Used in the late-stage functionalization and diversification of drug candidates, particularly for introducing methyl groups.
• Agrochemical Synthesis: Employed in creating active ingredients for crop protection products where specific methyl-substituted structures are required.
• Ligand & Catalyst Development: Serves as a reagent in the research and preparation of novel organometallic complexes and catalysts.
• Material Science Research: Applied in the synthesis of organic electronic materials and polymers with tailored properties.
• Chemical Library Production: Utilized in parallel and combinatorial chemistry for high-throughput synthesis of diverse compound libraries.

Basic Information

Product Name	Potassium Methyltrifluoroborate
CAS No.	1279123-64-6
Molecular Formula	CH3BF3K
Molecular Weight	127.94 g/mol
Synonyms	Methyltrifluoroborate Potassium Salt; Potassium Methyl-Trifluoroboronate; Potassium (Methyl)Trifluoroborate; Methylpotassium Trifluoroborane; Methyl-Boron, Trifluoro-, Potassium Salt; CH3BF3K; Methyl BF3K Salt; Potassium Trifluoro(Methyl)Borate
EINECS	Contact for details

Quality Control

Our Potassium Methyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) and in a desiccator for long-term storage to maintain optimal stability and reactivity. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (NMR/HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Potassium Content	Contact for details
Boron Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.