Description

Potassium Tetrahydro-2H-Pyran-4-Trifluoroborate is a high-purity organoboron reagent widely used in advanced organic synthesis. This compound is valued for its stability and reactivity as a key building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical development, and materials science.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A crucial boron reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and the pyranyl moiety.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing tetrahydropyran scaffolds.
• Agrochemical Development: Serves as a key intermediate in creating novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the synthesis of organic ligands, polymers, and advanced functional materials.
• Medicinal Chemistry & Drug Discovery: Facilitates the rapid exploration of chemical space in lead optimization and library synthesis.
• Academic & Industrial R&D: A standard reagent for methodological development in organic synthesis laboratories worldwide.

Basic Information

Item	Details
Product Name	Potassium Tetrahydro-2H-Pyran-4-Trifluoroborate
CAS No.	1279123-50-0
Molecular Formula	C5H8BF3KO
Molecular Weight	188.03 g/mol
Synonyms	Potassium (Tetrahydro-2H-pyran-4-yl)trifluoroborate; Potassium 4-(Trifluoroboranyl)tetrahydropyran; Tetrahydro-2H-pyran-4-yltrifluoroborate Potassium Salt; 4-(Trifluoroboranyl)tetrahydropyran Potassium Salt; THP-BF3K; Potassium 4-Trifluoroboranyltetrahydropyran; Potassium Tetrahydro-2H-pyran-4-yl-trifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium Tetrahydro-2H-Pyran-4-Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 13C) and HPLC analysis, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) and at a controlled room temperature (15-25°C) to maximize shelf life and maintain reagent integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
1H NMR Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.