Description

Thieno[2,3-D]Pyridazine-7-Carboxamide, 2-(3-Fluorophenyl)-4-[(3S)-3-Piperidinylamino]-, Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the research and development of novel therapeutic agents, particularly in kinase inhibitor programs. It is primarily targeted at pharmaceutical R&D departments, biotechnology firms, and CROs (Contract Research Organizations) engaged in medicinal chemistry and preclinical studies.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of targeted small-molecule drugs, especially kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to develop new chemical entities.
• Biochemical Assay Development: Employed as a reference standard or probe compound in high-throughput screening and enzyme inhibition assays.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and drug-receptor interactions.
• Process Chemistry & Scale-Up: Acts as a starting material for process development and the manufacture of Active Pharmaceutical Ingredients (APIs) under GMP conditions.

Basic Information

Product Name	Thieno[2,3-D]Pyridazine-7-Carboxamide, 2-(3-Fluorophenyl)-4-[(3S)-3-Piperidinylamino]-, Hydrochloride
CAS No.	1278405-51-8
Molecular Formula	C19H20FN5OS • HCl
Molecular Weight	421.92 g/mol (Free base: 385.46 g/mol)
Synonyms	2-(3-Fluorophenyl)-4-[(3S)-3-piperidinylamino]thieno[2,3-d]pyridazine-7-carboxamide hydrochloride; (S)-2-(3-Fluorophenyl)-4-(piperidin-3-ylamino)thieno[2,3-d]pyridazine-7-carboxamide hydrochloride; 1278405-51-8; UNII-9F8Q8Q6Q3F; Thienopyridazine carboxamide derivative; Kinase inhibitor intermediate; CAS 1278405-51-8
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for research and development. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and LC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.