Description

(2R)-5,7-Dimethoxyflavanone CAS NO 1277188-85-8 is a high-purity, enantiomerically pure flavanone derivative, a key chiral intermediate in advanced organic synthesis. This compound matters for its role in the research and development of novel pharmaceutical agents and bioactive natural product analogs, where stereochemical purity is critical for efficacy and safety. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of potential drug candidates, particularly in oncology and metabolic disease research.
• Biochemical Research: Used as a reference standard or probe in enzymatic and receptor-binding studies to investigate flavonoid bioactivity.
• Natural Product Synthesis: Serves as a key precursor in the semi-synthesis or total synthesis of complex natural flavonoids and their stereoisomers.
• Asymmetric Catalysis Studies: Employed as a substrate or ligand in the development and screening of new asymmetric catalytic reactions.
• Cosmeceutical R&D: Investigated for its potential antioxidant properties in the development of advanced skincare formulations.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry, medicinal chemistry, and phytochemistry.

Basic Information

Product Name	(2R)-5,7-Dimethoxyflavanone
CAS No.	1277188-85-8
Molecular Formula	C₁₇H₁₆O₄
Molecular Weight	284.31 g/mol
Synonyms	(R)-5,7-Dimethoxyflavanone; (2R)-5,7-Dimethoxy-2,3-dihydro-4H-1-benzopyran-4-one; (R)-5,7-Dimethoxy-2,3-dihydroflavone; (2R)-5,7-Dimethoxy-2-phenylchroman-4-one; Flavanone, 5,7-dimethoxy-, (2R)-; (R)-5,7-Dimethoxy-2-phenylchroman-4-one; (2R)-5,7-Dimethoxy-2,3-dihydro-4H-chromen-4-one
EINECS	Contact for details

Quality Control

Our (2R)-5,7-Dimethoxyflavanone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to prevent oxidation and ensure long-term stability. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.