Description

(R)-2-Morpholinecarboxylic Acid Hcl is a chiral building block of significant importance in modern synthetic chemistry. This compound serves as a key intermediate in the development of enantiomerically pure pharmaceuticals and agrochemicals, where the specific (R)-configuration is often critical for biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors engaged in asymmetric synthesis and active pharmaceutical ingredient (API) development.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of enantiomerically pure drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of chiral ligands for metal-catalyzed asymmetric reactions, enhancing stereoselectivity.
• Agrochemical Synthesis: Serves as a building block for the production of chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Peptidomimetics Research: Incorporated into the design of peptide analogs and conformationally constrained scaffolds for drug discovery.
• Academic & Process Chemistry: Utilized in research laboratories for method development and scaling up chiral synthetic routes.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring high optical purity intermediates.

Basic Information

Product Name	(R)-2-Morpholinecarboxylic Acid Hcl
CAS No.	1273577-14-2
Molecular Formula	C5H10ClNO3
Molecular Weight	167.59 g/mol
Synonyms	(R)-Morpholine-2-carboxylic acid hydrochloride; (2R)-Morpholine-2-carboxylic acid hydrochloride; (R)-2-Carboxymorpholine hydrochloride; (R)-Morpholine-2-carboxylic acid HCl salt; L-Morpholine-2-carboxylic acid hydrochloride (incorrect but common search term); (R)-2-Morpholinecarboxylic acid monohydrochloride; (2R)-4H-1,4-Oxazine-2-carboxylic acid, hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2-Morpholinecarboxylic Acid Hcl is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing parameters such as assay, enantiomeric excess, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.