Description

3-Chloro-4-Methoxy-5-(Trifluoromethyl)Benzoic Acid is a high-value, multi-functional aromatic carboxylic acid building block distinguished by its unique trifluoromethyl and methoxy substituents. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals where its structure imparts critical properties like metabolic stability and lipophilicity. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of drug candidates, especially in areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Active Ingredient Precursor: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for advanced electronic materials due to its aromatic core and halogen/alkoxy functional groups.
• Polymer Modification Agent: Employed to introduce functional side chains into polymers, altering their physical and chemical properties for specialty applications.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions, esterifications, and amide bond formations as a versatile carboxylic acid component.
• Chemical Research & Development: A valuable tool compound for medicinal chemistry and material science research in academic and industrial laboratories.

Basic Information

Item	Detail
Product Name	3-Chloro-4-Methoxy-5-(Trifluoromethyl)Benzoic Acid
CAS No.	1272528-86-5
Molecular Formula	C9H6ClF3O3
Molecular Weight	254.59 g/mol
Synonyms	3-Chloro-4-methoxy-5-(trifluoromethyl)benzoic acid; 5-(Trifluoromethyl)-3-chloro-4-methoxybenzoic acid; Benzoic acid, 3-chloro-4-methoxy-5-(trifluoromethyl)-; 3-Chloro-4-methoxy-alpha,alpha,α-trifluoro-m-toluic acid; 1272528-86-5; 3-Chloro-4-methoxy-5-trifluoromethylbenzoic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Methoxy-5-(Trifluoromethyl)Benzoic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.