Description

4-(Tributylstannyl)Quinoline is a specialized organotin compound featuring a quinoline heterocycle, serving as a versatile building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate for the Stille cross-coupling reaction, enabling the efficient formation of carbon-carbon bonds under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing complex molecules, including active pharmaceutical ingredients (APIs) and organic electronic materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require the quinoline scaffold for biological activity.
• Materials Science Research: Serves as a building block for creating organic semiconductors, light-emitting diodes (OLEDs), and other functional materials.
• Catalyst & Ligand Development: Employed in the preparation of novel organometallic catalysts and ligands for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and molecular probes for studying biological systems.
• Academic & R&D Laboratories: A valuable reagent for methodological development in synthetic organic chemistry and catalysis research.

Basic Information

Product Name	4-(Tributylstannyl)Quinoline
CAS No.	1272412-64-2
Molecular Formula	C21H33NSn
Molecular Weight	418.19 g/mol
Synonyms	4-Tributylstannylquinoline; Quinoline, 4-(tributylstannyl)-; Tributyl(quinolin-4-yl)stannane; 4-(Tributylstanny)chinolin; 4-Quinolyltributyltin; Stannane, tributyl(4-quinolinyl)-; 4-(Tributyltin)quinoline; 4-(SnBu3)Quinoline
EINECS	Contact for details

Quality Control

Our 4-(Tributylstannyl)Quinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and industrial applications. Each lot is analyzed using advanced techniques including NMR (1H, 13C, 119Sn), HPLC, and GC to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥95% (Typical: 97-99%)
Tin (Sn) Content	Calculated from formula
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.