Description

6-Bromo-3,4-Dihydro-2H-Chromene-3-Carbonitrile is a versatile and high-value brominated chromene derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular scaffold, featuring both a bromine substituent and a nitrile group, makes it an essential building block for constructing complex heterocyclic compounds. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive chromene core.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Academic & R&D: Employed in methodological studies and as a standard in organic synthesis research for constructing fused oxygen heterocycles.
• Ligand & Catalyst Development: The nitrile and bromine functionalities allow for its use in designing novel ligands for metal-catalyzed reactions.
• Fluorescent Probe Synthesis: The chromene structure can be utilized to develop fluorescent markers and sensors for biochemical applications.

Basic Information

Product Name	6-Bromo-3,4-Dihydro-2H-Chromene-3-Carbonitrile
CAS No.	1269293-22-2
Molecular Formula	C10H8BrNO
Molecular Weight	238.08 g/mol
Synonyms	6-Bromo-3,4-dihydro-2H-1-benzopyran-3-carbonitrile; 6-Bromo-3-cyano-3,4-dihydro-2H-chromene; 3-Cyano-6-bromo-3,4-dihydro-2H-chromene; 2H-1-Benzopyran-3-carbonitrile, 6-bromo-3,4-dihydro-; 6-Bromo-3,4-dihydro-2H-chromene-3-carbonitrile; 1269293-22-2
EINECS	Contact for details

Quality Control

Our 6-Bromo-3,4-Dihydro-2H-Chromene-3-Carbonitrile is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.