Description

1-Methyl-5-(Thiophen-3-Yl)-1H-Pyrazole is a high-purity heterocyclic organic compound featuring a pyrazole core substituted with a thiophene ring. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for complex chemical synthesis. It is primarily sought after by research institutions and fine chemical manufacturers engaged in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry research for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Serves as a core scaffold for developing new-generation pesticides and herbicides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and other electronic materials due to its conjugated thiophene-pyrazole system.
• Ligand and Catalyst Development: Acts as a building block for creating novel chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific heterocyclic frameworks.

Basic Information

Product Name	1-Methyl-5-(Thiophen-3-Yl)-1H-Pyrazole
CAS No.	1269292-87-6
Molecular Formula	C8H8N2S
Molecular Weight	164.23 g/mol
Synonyms	3-(1-Methyl-1H-pyrazol-5-yl)thiophene; 5-(Thiophen-3-yl)-1-methyl-1H-pyrazole; 1-Methyl-5-(3-thienyl)pyrazole; 1-Methyl-5-(thiophen-3-yl)-1H-pyrazole; 1-Methyl-5-(3-thienyl)-1H-pyrazole; 1-Methyl-5-(thiophene-3-yl)-1H-pyrazole
EINECS	Contact for details

Quality Control

Our production of 1-Methyl-5-(Thiophen-3-Yl)-1H-Pyrazole adheres to stringent GMP-like guidelines to ensure batch-to-batch consistency and high purity. Every lot undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.