Description

2-(2-Aminoethyl)-6-Phenyl-4,5-Dihydro-3(2H)-Pyridazinone Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1269288-52-9. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for central nervous system (CNS) and cardiovascular targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular diseases.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of biochemical tools and probes for studying enzyme inhibition and receptor binding.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and pharmacological research.

Basic Information

Product Name	2-(2-Aminoethyl)-6-Phenyl-4,5-Dihydro-3(2H)-Pyridazinone Hydrochloride
CAS No.	1269288-52-9
Molecular Formula	C12H16ClN3O
Molecular Weight	253.73 g/mol
Synonyms	6-Phenyl-2-(2-aminoethyl)-4,5-dihydro-3(2H)-pyridazinone hydrochloride; 2-(2-Aminoethyl)-6-phenyl-2,3-dihydro-4H-pyridazin-3-one hydrochloride; 6-Phenyl-2-(2-aminoethyl)-4,5-dihydropyridazin-3(2H)-one hydrochloride; 1269288-52-9; 2-(2-Aminoethyl)-6-phenyl-4,5-dihydro-3(2H)-pyridazinone HCl; 6-Phenyl-2-(2-aminoethyl)-4,5-dihydro-3(2H)-pyridazinone monohydrochloride
EINECS	Contact for details

Quality Control

Our 2-(2-Aminoethyl)-6-Phenyl-4,5-Dihydro-3(2H)-Pyridazinone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.