Description

4-Aminotetrahydro-n-Methyl-2H-Pyran-4-Carboxamide is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of novel, high-value active pharmaceutical ingredients (APIs). Pharmaceutical research and development teams, particularly those focused on central nervous system (CNS) agents and other therapeutic small molecules, require this high-purity intermediate to streamline their synthetic routes and ensure final product quality.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in neurological and psychiatric therapeutic areas.
• Agrochemical Research: Used in the development of new, more effective pesticides and herbicides with complex stereochemical requirements.
• Asymmetric Synthesis: Serves as a valuable precursor in catalytic asymmetric reactions to construct complex molecular architectures.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Fine Chemical Production: Integral to the multi-step synthesis of other high-value, specialty fine chemicals and advanced materials.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory research projects.

Basic Information

Product Name	4-Aminotetrahydro-n-Methyl-2H-Pyran-4-Carboxamide
CAS No.	1268883-06-2
Molecular Formula	C8H16N2O2
Molecular Weight	172.22 g/mol
Synonyms	4-Amino-4-(aminocarbonyl)-N-methyltetrahydro-2H-pyran; 4-Amino-N-methyltetrahydro-2H-pyran-4-carboxamide; 4-Carbamoyl-4-amino-N-methyltetrahydropyran; 4-Aminotetrahydro-2H-pyran-4-carboxamide, N-methyl-; (4R/S)-4-Amino-N-methyloxane-4-carboxamide (racemic mixture); Tetrahydro-2H-pyran-4-carboxamide, 4-amino-N-methyl-; 1268883-06-2
EINECS	Contact for details

Quality Control

Our 4-Aminotetrahydro-n-Methyl-2H-Pyran-4-Carboxamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.