Description

Cy7 Diacid is a near-infrared cyanine dye derivative featuring two carboxylic acid functional groups, enabling versatile bioconjugation. This compound is essential for developing advanced diagnostic and imaging agents due to its deep tissue penetration and high signal-to-noise ratio. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications such as fluorescence labeling, bioassay development, and in vivo imaging.

Application

• Fluorescent Probe Synthesis: Serves as a key intermediate for creating NIR fluorescent probes and sensors for biological detection.
• Bioconjugation & Labeling: The diacid groups allow covalent attachment to antibodies, peptides, proteins, and nanoparticles for targeted imaging.
• In Vivo Imaging: Used in the development of contrast agents for non-invasive deep-tissue fluorescence imaging in preclinical research.
• Bioassay Development: Employed in designing high-throughput screening (HTS) assays and diagnostic kits utilizing near-infrared fluorescence.
• Material Science: Incorporated into functional polymers and nanomaterials to impart fluorescence properties for tracking and sensing applications.
• Optical Device Research: Acts as a functional dye in the research and development of photonic devices and optical materials.

Basic Information

Product Name	Cy7 Diacid
CAS No.	1268616-88-1
Molecular Formula	C37H43N2O4+
Molecular Weight	579.75 g/mol
Synonyms	Cy7 Bis(carboxylic acid); 2-[7-[1,3-Dihydro-3,3-dimethyl-1-(4-sulfobutyl)-2H-indol-2-ylidene]-1,3,5-heptatrienyl]-3,3-dimethyl-1-(4-sulfobutyl)-3H-indolium-5-carboxylic acid; Sulfo-Cy7 diacid; Cyanine7 diacid; NIR Cy7 diacid; Heptamethine cyanine diacid; ICG derivative diacid
EINECS	Contact for details

Quality Control

Our Cy7 Diacid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and spectrophotometry for optical property verification. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. The product is hygroscopic (moisture-sensitive) and light-sensitive; desiccants are recommended for long-term storage. Keep container tightly sealed under an inert atmosphere when not in use to maintain stability.

Specification

Item	Specification
Appearance	Dark green to blue-green solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0% (Area %)
Water Content (KF)	≤5.0%
Absorption (λmax)	747 - 753 nm
Emission (λmax)	770 - 780 nm
Extinction Coefficient	≥ 190,000 L·mol⁻¹·cm⁻¹

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.