Description

4-Methoxymethyl-Tetrahydro-Pyran-4-Carbonitrile is a versatile heterocyclic nitrile building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring a tetrahydro-2H-pyran ring substituted with both a nitrile and a methoxymethyl group, makes it a valuable precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of monomers or additives for advanced polymers with specific thermal or mechanical properties.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-Methoxymethyl-Tetrahydro-Pyran-4-Carbonitrile
CAS No.	1268154-09-1
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	4-(Methoxymethyl)tetrahydro-2H-pyran-4-carbonitrile; Tetrahydro-4-(methoxymethyl)-2H-pyran-4-carbonitrile; 4-Cyano-4-(methoxymethyl)tetrahydropyran; 4-Methoxymethyl-4-cyanotetrahydropyran; 4-(Methoxymethyl)oxane-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Methoxymethyl-Tetrahydro-Pyran-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.