Description

1-[(3-Methoxyphenyl)Methyl]Cyclopropane-1-Carboxylic Acid is a high-value, synthetically derived carboxylic acid featuring a cyclopropane ring and a 3-methoxybenzyl substituent, making it a versatile chiral building block for advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where its unique sterically constrained structure is leveraged to modulate biological activity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel molecular entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used as a building block for developing advanced pesticides and herbicides, where the cyclopropane moiety can enhance stability and bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the synthesis of flavors, fragrances, and other high-value specialty chemicals requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, including ring-opening reactions and cross-coupling methodologies.
• Material Science Precursor: Potential use in synthesizing monomers for specialized polymers with tailored thermal and mechanical properties.

Basic Information

Product Name	1-[(3-Methoxyphenyl)Methyl]Cyclopropane-1-Carboxylic Acid
CAS No.	1267616-28-3
Molecular Formula	C12H14O3
Molecular Weight	206.24 g/mol
Synonyms	1-[(3-Methoxybenzyl)]cyclopropanecarboxylic Acid; 1-(3-Methoxybenzyl)cyclopropane-1-carboxylic Acid; Cyclopropanecarboxylic acid, 1-[(3-methoxyphenyl)methyl]-; 3-Methoxybenzylcyclopropanecarboxylic Acid; (3-Methoxybenzyl)cyclopropanecarboxylic Acid; 1-(3-Methoxybenzyl)-1-cyclopropanecarboxylic Acid; 1267616-28-3; m-Methoxybenzylcyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-[(3-Methoxyphenyl)Methyl]Cyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles to support your quality and regulatory requirements. Specifications can be tailored to meet specific R&D or cGMP intermediate needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation. Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0% (Area Percent)
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.