Description

1-Chloro-2-(cyclopropylmethoxy)-4-nitrobenzene is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated aromatic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables targeted molecular modifications. It is primarily utilized by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable building blocks for innovative synthesis pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research for developing new therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its nitro and chloro functional groups.
• Chemical Research & Development: Serves as a versatile substrate for organic synthesis, including cross-coupling reactions and functional group transformations in academic and industrial labs.
• Material Science Precursor: Potential use in the synthesis of specialty polymers, liquid crystals, or organic electronic materials due to its aromatic core and substituents.
• Dye & Pigment Intermediate: Can be utilized in the development of specialized nitro-aromatic dyes and colorants.

Basic Information

Product Name	1-Chloro-2-(Cyclopropylmethoxy)-4-Nitrobenzene
CAS No.	1265236-34-7
Molecular Formula	C10H10ClNO3
Molecular Weight	227.64 g/mol
Synonyms	2-Chloro-1-(cyclopropylmethoxy)-4-nitrobenzene; 4-Nitro-2-chloro-1-(cyclopropylmethoxy)benzene; Benzene, 1-chloro-2-(cyclopropylmethoxy)-4-nitro-; 1-Chloro-2-(cyclopropyloxymethyl)-4-nitrobenzene; (2-Chloro-4-nitrophenyl) cyclopropylmethyl ether
EINECS	Contact for details

Quality Control

Our 1-Chloro-2-(cyclopropylmethoxy)-4-nitrobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light) and should be handled under an inert atmosphere if prolonged exposure is expected.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.