Description

trans-3-Hydroxyhept-4-enoic acid is a chiral, unsaturated hydroxy fatty acid derivative of significant interest in advanced organic synthesis. Its unique structure, featuring both a hydroxyl group and a carbon-carbon double bond in a specific trans configuration, makes it a valuable versatile chiral building block for the construction of complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those with complex lipid-like structures or specific stereocenters.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and plant growth regulators where its unsaturated chain can be functionalized.
• Flavor & Fragrance Precursor: Serves as a starting material for the production of specific lactones or other aroma compounds due to its hydroxy acid functionality.
• Biochemical Research: Employed in studies of fatty acid metabolism, enzyme substrates, or as a standard in analytical method development.
• Polymer Chemistry: Acts as a monomer or co-monomer for the synthesis of specialized, functionalized polymers with tailored properties.
• Asymmetric Catalysis: Utilized as a substrate or ligand precursor in the development and testing of new chiral catalysts.

Basic Information

Product Name	trans-3-Hydroxyhept-4-enoic Acid
CAS No.	1263035-64-8
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(3R,4E)-3-Hydroxyhept-4-enoic Acid; (E)-3-Hydroxyhept-4-enoic Acid; trans-3-Hydroxy-4-heptenoic Acid; 3-Hydroxy-trans-4-heptenoic Acid; (3R)-3-Hydroxy-(4E)-heptenoic Acid; 4-Heptenoic acid, 3-hydroxy-, (E)-; Hept-4-enoic acid, 3-hydroxy-, (3R,4E)-
EINECS	Contact for details

Quality Control

Our production of trans-3-Hydroxyhept-4-enoic Acid adheres to stringent in-house quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, and NMR to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support development projects with custom synthesis and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.