Description

trans-4-(Methylamino)Tetrahydro-3-Furanol Hydrochloride is a high-purity pharmaceutical intermediate and chiral building block. This compound is valued for its defined stereochemistry and functional groups, making it a critical precursor in sophisticated organic syntheses. It is primarily utilized by research institutions and pharmaceutical manufacturers developing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates.
• API Synthesis: Used in the multi-step synthesis of complex active pharmaceutical ingredients, especially those containing tetrahydrofuran and amino alcohol motifs.
• Asymmetric Catalysis Research: Serves as a ligand precursor or a chiral pool starting material in catalytic reaction studies.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	trans-4-(Methylamino)Tetrahydro-3-Furanol Hydrochloride
CAS No.	1262769-93-6
Molecular Formula	C6H14ClNO2
Molecular Weight	167.63 g/mol
Synonyms	trans-4-(Methylamino)tetrahydrofuran-3-ol hydrochloride; (3R,4S)-4-(Methylamino)tetrahydrofuran-3-ol hydrochloride; (3S,4R)-4-(Methylamino)tetrahydrofuran-3-ol hydrochloride; 4-(Methylamino)-3-tetrahydrofuranol hydrochloride; Tetrahydro-3-furanol, 4-(methylamino)-, hydrochloride, trans-; 3-Furanol, tetrahydro-4-(methylamino)-, hydrochloride, trans-; 1262769-93-6; UNII-7D2V6K7W2I
EINECS	Contact for details

Quality Control

Our trans-4-(Methylamino)Tetrahydro-3-Furanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP starting material applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% de
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.