Description

(6Ar,10Ar)-1-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-6A,7,8,10A-Tetrahydro-6,6-Dimethyl-3-Pentyl-6H-Dibenzo[B,D]Pyran-9-Carboxylic Acid Ethyl Ester is a high-purity synthetic cannabinoid intermediate, specifically a protected derivative of a tetrahydrocannabinol (THC) analog. This compound is critical for pharmaceutical research and development, offering a precisely defined chemical scaffold for the synthesis of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical companies, and advanced chemical synthesis facilities engaged in cannabinoid receptor studies and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic pathway for novel cannabinoid-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a protected precursor for structure-activity relationship (SAR) studies targeting CB1 and CB2 receptors.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in cannabinoid synthesis.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for potential therapeutic candidates.
• Biochemical Research: Utilized in vitro studies to investigate cannabinoid receptor binding and downstream signaling pathways.
• Custom Synthesis: Starting material for the preparation of specialized, labeled (e.g., deuterated) cannabinoid analogs for advanced research.

Basic Information

Product Name	(6Ar,10Ar)-1-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-6A,7,8,10A-Tetrahydro-6,6-Dimethyl-3-Pentyl-6H-Dibenzo[B,D]Pyran-9-Carboxylic Acid Ethyl Ester
CAS No.	1262438-66-3
Molecular Formula	C31H48O4Si
Molecular Weight	512.80 g/mol
Synonyms	1-[(tert-Butyldimethylsilyl)oxy]-6a,7,8,10a-tetrahydro-6,6-dimethyl-3-pentyl-6H-dibenzo[b,d]pyran-9-carboxylic acid ethyl ester; Ethyl 1-[(tert-butyldimethylsilyl)oxy]-6a,7,8,10a-tetrahydro-6,6-dimethyl-3-pentyl-6H-dibenzo[b,d]pyran-9-carboxylate; TBDMS-protected THC analog ethyl ester; O-TBDMS THC-COOH ethyl ester; Cannabinoid intermediate 1262438-66-3; 9-Carbethoxy-1-O-TBDMS-δ6a,10a-THC
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. While produced under controlled conditions, this product is intended for research use and is not for human or veterinary therapeutic use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.