Description

2,2-Difluoroprop-1-Yltoluene-4-Sulphonate is a specialized organofluorine sulfonate ester, a key building block in advanced chemical synthesis. This compound is valued for its role as a versatile intermediate in the development of pharmaceuticals and agrochemicals, particularly where the introduction of a difluoromethyl or sulfonate ester group is required. It is essential for researchers and manufacturers in fine chemical, pharmaceutical R&D, and crop protection industries seeking to create novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules containing difluoromethyl ether or sulfonate ester functionalities.
• Agrochemical Synthesis: Used in the research and production of modern pesticides and herbicides, where the difluoroprop-yl group can improve metabolic stability and bioavailability.
• Material Science Research: Serves as a monomer or modifying agent in the development of specialty polymers and advanced materials with specific surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry for creating novel ligands and catalysts used in cross-coupling and fluorination reactions.
• Fluorine Chemistry Building Block: A valuable reagent for introducing fluorine atoms into complex organic molecules in medicinal and synthetic chemistry.

Basic Information

Item	Details
Product Name	2,2-Difluoroprop-1-Yltoluene-4-Sulphonate
CAS No.	1262400-01-0
Molecular Formula	C10H10F2O3S
Molecular Weight	248.25 g/mol
Synonyms	2,2-Difluoropropyl p-Toluenesulfonate; 1,1-Difluoropropan-2-yl Tosylate; p-Toluenesulfonic Acid 2,2-Difluoropropyl Ester; 4-Methylbenzenesulfonic Acid 2,2-Difluoroprop-1-yl Ester; 2,2-Difluoropropyl Tosylate; (2,2-Difluoropropyl) 4-methylbenzenesulfonate; DFPT; CAS 1262400-01-0
EINECS	Contact for details

Quality Control

Our 2,2-Difluoroprop-1-Yltoluene-4-Sulphonate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.