Description

2-Chloro-4-(3-Chlorophenyl)Benzoic Acid is a specialized chlorinated biphenyl carboxylic acid derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and high-performance materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel compounds and scaling up synthetic routes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its biphenyl core for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, or polymers requiring specific chlorinated aromatic units.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic and Industrial R&D: Utilized in exploratory chemistry for method development and creating compound libraries for high-throughput screening.

Basic Information

Product Name	2-Chloro-4-(3-Chlorophenyl)Benzoic Acid
CAS No.	1261981-20-7
Molecular Formula	C13H8Cl2O2
Molecular Weight	267.11 g/mol
Synonyms	2-Chloro-4-(3-chlorophenyl)benzoic acid; [1,1'-Biphenyl]-2-carboxylic acid, 2'-chloro-3'-chloro- (alternative numbering); 3'-Chloro-2-chloro[1,1'-biphenyl]-4-carboxylic acid; 4-(3-Chlorophenyl)-2-chlorobenzoic acid; 2-Chloro-4-(3-chlorophenyl)benzoic Acid (primary IUPAC-style); Biphenyl-2-carboxylic acid, 2,3'-dichloro- derivative; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(3-Chlorophenyl)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with batch-specific data are available upon request, providing full traceability and compliance documentation for your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.