Description

4-(4-Chlorophenyl)-2-Fluorophenol is a specialized fluorinated phenolic compound that serves as a high-value intermediate in advanced organic synthesis. Its unique structure, featuring both chloro and fluoro substituents on a biphenyl-like scaffold, makes it a critical building block for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in drug discovery and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Used in the research and production of fluorinated liquid crystals for advanced display technologies.
• Polymer Science: Monomer or modifier for engineering plastics and high-performance polymers to impart specific thermal or chemical resistance.
• Organic Electronics: Intermediate in the development of organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Chemical Research: Versatile scaffold in medicinal and synthetic chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	4-(4-Chlorophenyl)-2-Fluorophenol
CAS No.	1261944-84-6
Molecular Formula	C12H8ClFO
Molecular Weight	222.64 g/mol
Synonyms	2-Fluoro-4'-(4-chlorophenyl)phenol; 4'-Chloro-2-fluoro[1,1'-biphenyl]-4-ol; (4-Chlorophenyl)-(2-fluoro-4-hydroxyphenyl)methane; 2-Fluoro-4-(4-chlorophenyl)phenol; 4-(4-Chlorophenyl)-2-fluorophenol; 4-(p-Chlorophenyl)-2-fluorophenol; 2-Fluoro-4-(p-chlorophenyl)phenol
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Chlorophenyl)-2-Fluorophenol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support cGMP and ISO standards for traceability and consistency, which is critical for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.