Description

2-Iodo-5-Bromobenzyl Chloride is a versatile and highly functionalized halogenated benzyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring three distinct halogen substituents, makes it an exceptionally valuable intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions, nucleophilic substitutions, and as a precursor to various functional groups.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the benzyl chloride moiety acts as a reactive handle for further derivatization.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis, such as Suzuki-Miyaura or Buchwald-Hartwig cross-couplings.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and polymers where halogen atoms influence material properties.
• Custom Chemical Synthesis: A valuable reagent for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds for client projects.

Basic Information

Product Name	2-Iodo-5-Bromobenzyl Chloride
CAS No.	1261817-10-0
Molecular Formula	C7H5BrClI
Molecular Weight	331.38 g/mol
Synonyms	1-(Chloromethyl)-2-iodo-5-bromobenzene; 5-Bromo-2-iodobenzyl Chloride; (5-Bromo-2-iodophenyl)methyl Chloride; α-Chloro-5-bromo-2-iodotoluene; 2-Iodo-5-bromo-α-chlorotoluene; Benzene, 1-(chloromethyl)-2-iodo-5-bromo-; 5-Bromo-2-iodo-benzylchloride
EINECS	Contact for details

Quality Control

Every batch of 2-Iodo-5-Bromobenzyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality commitment supports compliance in cGMP and ISO 9001 environments where documentation and traceability are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.