Description

5-Nitro-3-(4-Trifluoromethoxyphenyl)Benzoic Acid is a high-value, multi-functional aromatic carboxylic acid derivative, distinguished by its nitro and trifluoromethoxy substituents. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry, enabling the development of novel active ingredients. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating compounds with specific biological and physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the nitro and trifluoromethoxy groups.
• Liquid Crystal & OLED Material Synthesis: Used in the research and production of advanced electronic materials, where its aromatic core and fluorine content contribute to desired electronic and optical properties.
• Organic Synthesis & Catalysis: Acts as a versatile reagent in coupling reactions (e.g., Suzuki, Heck) and as a ligand precursor in catalytic systems due to its functionalized benzoic acid structure.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in biochemical research to study protein interactions and enzyme mechanisms.
• Polymer Modification: Incorporated into polymer chains to impart specific characteristics like hydrophobicity, chemical resistance, or altered thermal stability.

Basic Information

Product Name	5-Nitro-3-(4-Trifluoromethoxyphenyl)Benzoic Acid
CAS No.	1261782-84-6
Molecular Formula	C14H8F3NO5
Molecular Weight	327.21 g/mol
Synonyms	3-(4-(Trifluoromethoxy)phenyl)-5-nitrobenzoic acid; 5-Nitro-3-[4-(trifluoromethoxy)phenyl]benzoic acid; Benzoic acid, 5-nitro-3-[4-(trifluoromethoxy)phenyl]-; [4-(Trifluoromethoxy)phenyl]-5-nitro-m-benzoic acid
EINECS	Contact for details

Quality Control

Our production of 5-Nitro-3-(4-Trifluoromethoxyphenyl)Benzoic Acid adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions, such as in a desiccator or under an inert atmosphere, to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.