Description

2-Bromo-3-Iodobenzyl Bromide is a versatile and highly functionalized halogenated benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of three distinct halogens, which provide multiple, orthogonal sites for selective cross-coupling and substitution reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for constructing complex molecular architectures and developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogen atoms for structural diversity.
• Material Science & Liquid Crystals: Serves as a building block for creating advanced organic electronic materials, ligands for catalysts, and components for liquid crystal displays (LCDs).
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings, where the iodine and bromine atoms offer differentiated reactivity for sequential functionalization.
• Organic Synthesis & Research: Employed in academic and industrial R&D for constructing complex polycyclic aromatic compounds and other specialty chemicals.

Basic Information

Product Name	2-Bromo-3-Iodobenzyl Bromide
CAS No.	1261757-20-3
Molecular Formula	C7H5Br2I
Molecular Weight	390.83 g/mol
Synonyms	1-(Bromomethyl)-2-bromo-3-iodobenzene; (2-Bromo-3-iodophenyl)methyl Bromide; α,2-Dibromo-3-iodotoluene; 2-Bromo-3-iodo-α-bromotoluene; Benzene, 1-(bromomethyl)-2-bromo-3-iodo-; 2-Bromo-3-iodobenzylbromide
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-Iodobenzyl Bromide is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.