Description

2-Chloro-6-(Trifluoromethoxy)Aniline, 97% is a high-purity aromatic amine derivative featuring both chloro and trifluoromethoxy substituents, making it a versatile and valuable building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring a reliable, high-quality intermediate to introduce specific functional groups into complex molecular architectures. It is primarily sought after by the pharmaceutical and agrochemical industries for the development of novel active ingredients, where its unique halogenated structure is critical for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for creating molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex, high-performance colorants and functional dyes.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing C-N bonds in complex molecules.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-Chloro-6-(Trifluoromethoxy)Aniline, 97%
CAS No.	1261673-70-4
Molecular Formula	C7H5ClF3NO
Molecular Weight	211.57 g/mol
Synonyms	2-Chloro-6-(trifluoromethoxy)benzenamine; 1-Amino-2-chloro-6-(trifluoromethoxy)benzene; 2-Chloro-α,α,α-trifluoro-o-anisidine; 6-Amino-3-chlorobenzotrifluoride methyl ether; Benzenamine, 2-chloro-6-(trifluoromethoxy)-; 2-Chloro-6-trifluoromethoxyaniline
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(Trifluoromethoxy)Aniline, 97% is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the specified standards. A Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.