Description

5-Amino-2-Chlorophenylacetic Acid is a high-purity, versatile organic intermediate of significant importance in advanced chemical synthesis. Its unique structure, featuring both an amino and a carboxylic acid functional group on a chlorinated aromatic ring, makes it a critical building block for creating complex molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogenated aniline core.
• Dye and Pigment Manufacturing: Serves as a starting material for synthesizing specialized azo dyes and high-performance pigments due to its reactive amine group.
• Ligand and Catalyst Development: Employed in academic and industrial research to create novel chelating ligands for metal catalysts used in asymmetric synthesis.
• Peptidomimetic Research: The phenylacetic acid moiety makes it a valuable scaffold for designing and synthesizing peptide analogs and mimetics in drug discovery.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	5-Amino-2-Chlorophenylacetic Acid
CAS No.	1261566-24-8
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	2-Chloro-5-aminophenylacetic Acid; (5-Amino-2-chlorophenyl)acetic Acid; 2-Chloro-5-aminobenzeneacetic Acid; 5-Amino-2-chlorobenzeneacetic Acid; 2-(5-Amino-2-chlorophenyl)acetic Acid; 5-Amino-o-chlorophenylacetic Acid; 1261566-24-8
EINECS	Contact for details

Quality Control

Every batch of 5-Amino-2-Chlorophenylacetic Acid is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure consistency and high purity. Standard quality parameters include identity confirmation (IR, NMR), assay (HPLC), and control of specific impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.