Description

5-(Aminomethyl)-2-Chlorobenzonitrile is a versatile and high-value aromatic nitrile building block featuring both an aminomethyl and a chloro substituent. This bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for constructing active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer and Material Science: Incorporated into polymer backbones or as a functional modifier to impart specific chemical or physical properties to advanced materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries for screening.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized colorants and functional dyes due to its aromatic core and modifiable functional groups.

Basic Information

Product Name	5-(Aminomethyl)-2-Chlorobenzonitrile
CAS No.	1261499-40-4
Molecular Formula	C8H7ClN2
Molecular Weight	166.61 g/mol
Synonyms	2-Chloro-5-(aminomethyl)benzonitrile; 2-Chloro-5-cyanobenzylamine; (2-Chloro-5-cyanophenyl)methanamine; 5-(Aminomethyl)-2-chlorobenzene-1-carbonitrile; 2-Chloro-5-(aminomethyl)benzenecarbonitrile; Benzonitrile, 5-(aminomethyl)-2-chloro-; 1261499-40-4
EINECS	Contact for details

Quality Control

Our 5-(Aminomethyl)-2-Chlorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.