Description

3,3-Difluorocyclopentaecarboxylic Acid is a high-value fluorinated carboxylic acid building block, distinguished by its unique cyclopentane ring structure. This compound is critical for introducing difluoromethylene groups into target molecules, significantly altering their physicochemical and metabolic properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for specialty polymers, liquid crystals, and advanced organic electronic materials requiring fluorinated components.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex, fluorinated organic molecules via reactions such as esterification, amide coupling, and decarboxylative cross-coupling.
• Fluorine-19 NMR Spectroscopy: Can be used as a reference standard or probe in analytical chemistry due to the distinct NMR signature of its fluorine atoms.

Basic Information

Product Name	3,3-Difluorocyclopentaecarboxylic Acid
CAS No.	1260897-05-9
Molecular Formula	C6H6F2O2
Molecular Weight	148.11 g/mol
Synonyms	3,3-Difluorocyclopentane-1-carboxylic Acid; 3,3-Difluorocyclopentanecarboxylic Acid; Cyclopentanecarboxylic acid, 3,3-difluoro-; 1-Carboxy-3,3-difluorocyclopentane; 1260897-05-9
EINECS	Contact for details

Quality Control

Every batch of 3,3-Difluorocyclopentaecarboxylic Acid is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. Due to its carboxylic acid nature and sensitivity to fluoride/strong alkali, ensure proper segregation in storage areas.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.