Description

8-Bromo-Isochroman-4-One is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure makes it a valuable precursor for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the preparation of novel herbicides, fungicides, and insecticides requiring specific brominated heterocyclic motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and advanced polymers with unique properties.
• Chemical Biology Probes: Utilized as a building block for developing activity-based probes and other tools for studying biological systems.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	8-Bromo-Isochroman-4-One
CAS No.	1260803-24-4
Molecular Formula	C9H7BrO2
Molecular Weight	227.06 g/mol
Synonyms	8-Bromoisochroman-4-one; 8-Bromo-3,4-dihydro-1H-2-benzopyran-4-one; 4-Isochromanone, 8-bromo-; 1260803-24-4; 8-Bromo-3,4-dihydroisochromen-4-one; 8-Bromo-4H-isochromen-4-one; 8-Bromochroman-4-one (related structure)
EINECS	Contact for details

Quality Control

Our 8-Bromo-Isochroman-4-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports your R&D and scale-up processes with reliable, traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.