Description

1-(4-Chloro-2-Fluorophenyl)Cyclopentane-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its role as a critical building block in modern medicinal chemistry, enabling the development of novel therapeutic agents. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for process development and commercial-scale production.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel small-molecule drugs, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor for developing new-generation herbicides and pesticides with enhanced efficacy and selectivity.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring new chemical entities and reaction pathways in organic synthesis.
• API Process Development: Employed in scaling up and optimizing synthetic routes for Active Pharmaceutical Ingredients (APIs) under cGMP conditions.
• Ligand & Catalyst Preparation: Can be utilized to synthesize specialized ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	1-(4-Chloro-2-Fluorophenyl)Cyclopentane-1-Carboxylic Acid
CAS No.	1260775-49-2
Molecular Formula	C₁₂H₁₂ClFO₂
Molecular Weight	242.67 g/mol
Synonyms	1-(4-Chloro-2-fluorophenyl)cyclopentanecarboxylic acid; 1-(4-Chloro-2-fluorophenyl)cyclopentane-1-carboxylic acid; Cyclopentanecarboxylic acid, 1-(4-chloro-2-fluorophenyl)-; 1260775-49-2; 4-Chloro-2-fluoro-α-(1-cyclopentyl)benzenecarboxylic acid; 1-(4-Chloro-2-fluorophenyl)-1-cyclopentanecarboxylic acid; 1-(4-Chloro-2-fluorophenyl)cyclopentane carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-2-Fluorophenyl)Cyclopentane-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.