Description

Amino-(Tetrahydro-Pyran-3-Yl)-Acetic Acid is a high-purity chiral building block and advanced pharmaceutical intermediate of significant commercial interest. Its unique structure, featuring a tetrahydro-2H-pyran ring linked to an amino acid moiety, makes it a valuable synthon for constructing complex molecules with specific stereochemistry. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients, including potential protease inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in the development of protease inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the research and development of new pesticides and herbicides, where its structural motif can contribute to biological activity.
• Peptidomimetics: Serves as a constrained, non-natural amino acid analog in the design of peptidomimetic compounds to enhance metabolic stability and bioavailability.
• Chemical Biology Probes: Employed in the synthesis of specialized probes and ligands for studying enzyme function and biological pathways.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in asymmetric synthesis to induce stereoselectivity in chemical reactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract manufacturing organizations (CMOs) serving the life sciences industry.

Basic Information

Product Name	Amino-(Tetrahydro-Pyran-3-Yl)-Acetic Acid
CAS No.	1260638-48-9
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	2-Amino-2-(tetrahydro-2H-pyran-3-yl)acetic acid; (Tetrahydro-2H-pyran-3-yl)glycine; 3-Pyranylglycine; Amino(tetrahydro-2H-pyran-3-yl)acetic acid; (3-Tetrahydropyranyl)glycine; 2-Amino-2-(oxan-3-yl)acetic acid (IUPAC); Glycine, N-(tetrahydro-2H-pyran-3-yl)-; 1260638-48-9
EINECS	Contact for details

Quality Control

Every batch of Amino-(Tetrahydro-Pyran-3-Yl)-Acetic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with specifications for chiral purity, residual solvents, and heavy metals available. Certificates of Analysis (COA) are provided with each shipment, and we support customer audits and regulatory documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.