Description

(3S)-3,4-Dihydro-2H-1-Benzopyran-3-Carboxylic Acid is a chiral, non-racemic benzopyran derivative that serves as a critical synthetic intermediate and building block in advanced organic synthesis. Its value lies in its defined stereochemistry and functional groups, which enable the construction of complex molecules with high enantiomeric purity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds. The CAS number for this specific stereoisomer is 1260611-90-2.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides, where specific stereochemistry can impact biological activity and environmental safety.
• Asymmetric Synthesis: Serves as a versatile starting material or chiral auxiliary in catalytic asymmetric reactions to create other high-value chiral compounds.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require precise stereochemical control.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research within university and corporate laboratories.

Basic Information

Product Name	(3S)-3,4-Dihydro-2H-1-Benzopyran-3-Carboxylic Acid
CAS No.	1260611-90-2
Molecular Formula	C10H10O3
Molecular Weight	178.18 g/mol
Synonyms	(3S)-3,4-Dihydro-2H-chromene-3-carboxylic acid; (S)-3,4-Dihydro-2H-1-benzopyran-3-carboxylic acid; (S)-Chroman-3-carboxylic acid; (3S)-Chroman-3-carboxylic acid; (S)-3-Chromancarboxylic acid; 1260611-90-2; (S)-3,4-Dihydro-2H-chromene-3-carboxylic acid
EINECS	Contact for details

Quality Control

We supply (3S)-3,4-Dihydro-2H-1-Benzopyran-3-Carboxylic Acid in high-purity grades suitable for research and cGMP manufacturing. Our products undergo rigorous quality testing to ensure compliance with industry standards, including chiral purity verification. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing parameters such as assay, enantiomeric excess (ee), and impurity profiles. Certificates are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.