Description

(S)-6-Fluorochroman-4-Amine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is critical for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) targeting central nervous system and cardiovascular disorders. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of enantiomerically pure drugs.
• Organic Synthesis Building Block: Used in asymmetric synthesis for constructing complex chroman-based molecular architectures.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in API manufacturing.
• Preclinical Development: Used in the synthesis of candidate compounds for pharmacological and toxicological evaluation.

Basic Information

Product Name	(S)-6-Fluorochroman-4-Amine Hydrochloride
CAS No.	1260609-97-9
Molecular Formula	C10H13ClFNO
Molecular Weight	217.67 g/mol
Synonyms	(4S)-6-Fluoro-3,4-dihydro-2H-1-benzopyran-4-amine hydrochloride; (S)-6-Fluoro-3,4-dihydro-2H-chromen-4-amine hydrochloride; (S)-6-Fluorochroman-4-amine HCl; 6-Fluorochroman-4-amine hydrochloride, (S)-; (S)-4-Amino-6-fluorochroman hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-6-Fluorochroman-4-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept under inert conditions after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.