Description

(R)-Chroman-3-Carboxylic Acid CAS NO 1260609-71-9 is a high-purity chiral building block and key synthetic intermediate of significant value in advanced organic synthesis. Its enantiomerically pure structure makes it indispensable for the development of optically active compounds, particularly in the pharmaceutical sector. This product is essential for researchers and manufacturers in medicinal chemistry, agrochemical development, and fine chemical synthesis who require reliable, high-quality chiral intermediates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in therapeutic areas targeting specific enantiomeric activity.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to introduce the chroman carboxylic acid moiety into potential drug candidates.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the synthesis of complex, high-value specialty chemicals where optical purity is a critical performance parameter.
• Ligand and Catalyst Development: Useful for constructing chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(R)-Chroman-3-Carboxylic Acid
CAS No.	1260609-71-9
Molecular Formula	C10H10O3
Molecular Weight	178.18 g/mol
Synonyms	(R)-3-Chromancarboxylic Acid; (R)-3,4-Dihydro-2H-1-benzopyran-3-carboxylic Acid; (R)-2,3-Dihydro-4H-chromene-3-carboxylic Acid; (3R)-3,4-Dihydro-2H-chromene-3-carboxylic Acid; (R)-Chroman-3-carboxylic acid; (R)-3-Carboxychroman; (R)-3-Chromanecarboxylic Acid; (R)-3,4-Dihydro-2H-1-benzopyran-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our (R)-Chroman-3-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and mass spectrometry for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.