Description

1-(4-Fluoronaphthalen-1-Yl)Ethanamine is a specialized fluorinated naphthalene derivative serving as a high-value building block in advanced organic synthesis. This compound is critical for pharmaceutical and agrochemical research, enabling the introduction of both the fluoronaphthyl moiety and a primary amine functional group into target molecules. It is primarily utilized by R&D chemists and process development scientists in the life sciences and material science sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides that leverage the fluoronaphthalene scaffold for enhanced bioactivity.
• Material Science: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its rigid, fluorinated aromatic structure.
• Chemical Biology & Proteomics: Employed as a labeling reagent or a linker component in the design of chemical probes and affinity tags.
• Academic & Contract Research: Essential for methodological development in organic chemistry and catalysis studies involving fluorinated arenes.

Basic Information

Product Name	1-(4-Fluoronaphthalen-1-Yl)Ethanamine
CAS No.	1260486-39-2
Molecular Formula	C₁₂H₁₂FN
Molecular Weight	189.23 g/mol
Synonyms	1-(1-Aminoethyl)-4-fluoronaphthalene; 4-Fluoro-1-(1-aminoethyl)naphthalene; 1-(4-Fluoro-1-naphthyl)ethanamine; N-(4-Fluoronaphthalen-1-yl)ethanamine; α-Methyl-4-fluoro-1-naphthalenemethylamine; 1-(4-Fluoronaphth-1-yl)ethylamine; 4-Fluoro-N-(1-aminoethyl)naphthalene
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoronaphthalen-1-Yl)Ethanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.