Description

4-Nitro-1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-Pyrazole is a specialized pyrazole derivative featuring a nitro group and a silyl-protected hydroxymethyl moiety, making it a valuable synthetic intermediate. This compound matters for its role as a key building block in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), fine chemicals, and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, especially those targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Fine Chemical Synthesis: Acts as a versatile building block for constructing complex molecules in custom synthesis and process chemistry.
• Material Science Research: Potential use in the development of advanced organic materials and ligands for catalysis.
• Academic & Industrial R&D: Employed in research laboratories for methodological studies and the exploration of new chemical reactions.

Basic Information

Product Name	4-Nitro-1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-Pyrazole
CAS No.	1260160-79-9
Molecular Formula	C10H19N3O3Si
Molecular Weight	257.36 g/mol
Synonyms	1-[(2-Trimethylsilyl)ethoxymethyl]-4-nitropyrazole; 4-Nitro-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-pyrazole; 1H-Pyrazole, 4-nitro-1-[[2-(trimethylsilyl)ethoxy]methyl]-; 4-Nitro-1-((2-(trimethylsilyl)ethoxy)methyl)pyrazole; 4-Nitro-1-SEM-pyrazole; SEM-Protected 4-Nitropyrazole
EINECS	Contact for details

Quality Control

Our 4-Nitro-1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-Pyrazole is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity, the product should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.