Description

5,8-Dichloro-3,4-Dihydro-4-Methyl-2H-Pyridazino[4,5-B][1,4]Oxazine is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block of significant interest in modern organic synthesis. Its complex fused-ring structure makes it a valuable precursor for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, process development, and the synthesis of new chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Agrochemical Research: Serves as a precursor for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique pyridazine-oxazine scaffold.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of target molecules.
• Chemical Biology: Acts as a molecular probe or a core structure in the design of enzyme inhibitors and receptor modulators.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	5,8-Dichloro-3,4-Dihydro-4-Methyl-2H-Pyridazino[4,5-B][1,4]Oxazine
CAS No.	1259224-16-2
Molecular Formula	C8H7Cl2N3O
Molecular Weight	232.07 g/mol
Synonyms	5,8-Dichloro-4-methyl-3,4-dihydro-2H-pyridazino[4,5-b][1,4]oxazine; 2H-Pyridazino[4,5-b][1,4]oxazine, 5,8-dichloro-3,4-dihydro-4-methyl-; 5,8-Dichloro-4-methyl-2H,3H,4H-pyridazino[4,5-b][1,4]oxazine; 1259224-16-2; Pyridazinooxazine derivative
EINECS	Contact for details

Quality Control

Our 5,8-Dichloro-3,4-Dihydro-4-Methyl-2H-Pyridazino[4,5-B][1,4]Oxazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.