Description

Potassium Trifluoro(1-Methyl-1H-Pyrazol-5-Yl)Borate is a specialized organoboron reagent, specifically a potassium trifluoroborate salt, valued for its enhanced stability and handling properties compared to traditional boronic acids. This compound serves as a critical building block in modern synthetic chemistry, particularly in transition-metal-catalyzed cross-coupling reactions like the Suzuki-Miyaura reaction. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific pyrazole-containing structures.
• Materials Science Research: Employed in the creation of organic electronic materials, such as those used in OLEDs and organic photovoltaics, where precise molecular engineering is crucial.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and bio-conjugates for diagnostic and research applications.
• Scale-up Process Chemistry: Its improved stability makes it suitable for kilogram-scale manufacturing processes in fine chemical production.

Basic Information

Product Name	Potassium Trifluoro(1-Methyl-1H-Pyrazol-5-Yl)Borate
CAS No.	1258323-45-3
Molecular Formula	C4H5BF3KN2
Molecular Weight	187.99 g/mol
Synonyms	Potassium (1-Methyl-1H-pyrazol-5-yl)trifluoroborate; (1-Methyl-1H-pyrazol-5-yl)trifluoroborate Potassium Salt; 1-Methyl-1H-pyrazole-5-trifluoroboronic acid potassium salt; 5-Trifluoroboratomethyl-1H-pyrazole Potassium Salt; Potassium 1-Methyl-5-pyrazolyltrifluoroborate; K-1-Methyl-5-pyrazolyl-BF3; 1-Methyl-5-pyrazole trifluoroborate potassium
EINECS	Contact for details

Quality Control

Our Potassium Trifluoro(1-Methyl-1H-Pyrazol-5-Yl)Borate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B), HPLC for purity, and elemental analysis, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) in a desiccator for long-term storage to maintain stability and purity. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
11B NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.