Description

2-Chlorocyclopropanecarboxylic Acid is a versatile and synthetically valuable cyclopropane derivative, serving as a key chiral building block in advanced organic synthesis. Its unique strained-ring structure, functionalized with both a carboxylic acid and a chlorine substituent, makes it an essential precursor for constructing complex molecular architectures. This high-purity intermediate is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the cyclopropane ring contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized monomers and polymers with unique thermal or mechanical properties.
• Chemical Biology Probes: Utilized to incorporate the rigid cyclopropane scaffold into molecular probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	2-Chlorocyclopropanecarboxylic Acid
CAS No.	1258298-11-1
Molecular Formula	C4H5ClO2
Molecular Weight	120.54 g/mol
Synonyms	2-Chlorocyclopropane-1-carboxylic Acid; (1R,2S)-2-Chlorocyclopropanecarboxylic Acid (enantiomer); (1S,2R)-2-Chlorocyclopropanecarboxylic Acid (enantiomer); rac-2-Chlorocyclopropanecarboxylic Acid; 2-Chloro-1-cyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 2-chloro-
EINECS	Contact for details

Quality Control

Every batch of 2-Chlorocyclopropanecarboxylic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure the material meets the precise requirements of your research or process development. Certificates of Analysis (COA) detailing purity, enantiomeric excess (where applicable), and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation (for chiral grades)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.