Description

2-(2-Bromo-5-Chlorophenoxy)Methyltetrahydro-2H-Pyran is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated phenoxy-tetrahydropyran structure. This compound is critical for research and development chemists seeking to synthesize novel active pharmaceutical ingredients (APIs) with specific biological activity profiles. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in medicinal chemistry research for new small molecule therapies.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic moiety.
• Organic Synthesis Research: Used in academic and industrial R&D laboratories for constructing complex heterocyclic frameworks and studying structure-activity relationships (SAR).
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers or functional materials requiring specific halogenated aromatic ether components.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	2-(2-Bromo-5-Chlorophenoxy)Methyltetrahydro-2H-Pyran
CAS No.	1257664-96-2
Molecular Formula	C12H14BrClO2
Molecular Weight	305.60 g/mol
Synonyms	2-[(2-Bromo-5-chlorophenoxy)methyl]oxane; Tetrahydro-2H-pyran-2-ylmethyl 2-bromo-5-chlorophenyl ether; 2-(2-Bromo-5-chlorophenoxymethyl)tetrahydropyran; 2-((2-Bromo-5-chlorophenoxy)methyl)tetrahydro-2H-pyran; Bromochlorophenoxy methyl tetrahydropyran; BCPM-THP; 1257664-96-2
EINECS	Contact for details

Quality Control

Our 2-(2-Bromo-5-Chlorophenoxy)Methyltetrahydro-2H-Pyran is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, GC, and NMR. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.