Description

4-Bromo-3-Cyclopropyl-1-Methyl-1H-Pyrazole is a high-purity, functionalized pyrazole derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of a bromine substituent and a cyclopropyl group, which are key motifs for introducing structural complexity and modulating physicochemical properties in target molecules. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drug candidates, especially in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropyl moiety often enhances biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized N-heterocyclic ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of functional organic materials and advanced polymers with tailored properties.
• Chemical Biology Probes: Utilized to construct molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-Bromo-3-Cyclopropyl-1-Methyl-1H-Pyrazole
CAS No.	1257637-80-1
Molecular Formula	C7H9BrN2
Molecular Weight	201.07 g/mol
Synonyms	4-Bromo-3-cyclopropyl-1-methylpyrazole; 1-Methyl-4-bromo-3-cyclopropyl-1H-pyrazole; 3-Cyclopropyl-1-methyl-4-bromo-1H-pyrazole; 4-Bromo-3-cyclopropyl-1-methyl-1H-pyrazole; 1H-Pyrazole, 4-bromo-3-cyclopropyl-1-methyl-; 1257637-80-1 (CAS); 4-Br-3-Cyclopropyl-1-Me-Pyrazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Cyclopropyl-1-Methyl-1H-Pyrazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.