Description

5-Bromo-3-(Trifluoromethoxy)Phenylene-1,2-Diamine is a high-purity aromatic diamine derivative featuring bromine and trifluoromethoxy substituents. This compound is a critical advanced pharmaceutical intermediate and versatile building block for the synthesis of complex organic molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the biological activity of the diamine and halogenated aryl structure.
• Polymer & Material Science: Monomer for the production of high-performance polyimides, polyamides, and other specialty polymers requiring thermal stability and chemical resistance.
• Ligand & Catalyst Development: Used to synthesize chelating ligands for metal-organic frameworks (MOFs) and homogeneous catalysis applications.
• Dye & Pigment Intermediate: Serves as a starting material for creating complex organic dyes and pigments, especially azo dyes and colorants.
• Research & Development: Essential compound for academic and industrial research in medicinal chemistry and organic synthesis.

Basic Information

Item	Detail
Product Name	5-Bromo-3-(Trifluoromethoxy)Phenylene-1,2-Diamine
CAS No.	1257535-16-2
Molecular Formula	C7H6BrF3N2O
Molecular Weight	271.04 g/mol
Synonyms	5-Bromo-3-(trifluoromethoxy)benzene-1,2-diamine; 1,2-Diamino-5-bromo-3-(trifluoromethoxy)benzene; 2-Amino-4-bromo-6-(trifluoromethoxy)aniline; 4-Bromo-2-(trifluoromethoxy)-1,3-benzenediamine; 5-Bromo-3-(trifluoromethoxy)-1,2-phenylenediamine; 5-Bromo-3-(trifluoromethoxy)benzene-1,2-diyldiamine; 5-Bromo-3-(trifluoromethoxy)-o-phenylenediamine
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-(Trifluoromethoxy)Phenylene-1,2-Diamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.