Description

5-Bromo-2-Chloro-6-Methyl-Nicotinic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its precise halogen substitution pattern, which enables selective derivatization in complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging its halogenated nicotinic acid scaffold.
• Ligand and Catalyst Development: Serves as a versatile building block for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and organic semiconductors.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke intermediates under cGMP or research-grade conditions.
• Academic and R&D Laboratories: Used in medicinal chemistry and synthetic methodology research for exploring new chemical spaces.

Basic Information

Product Name	5-Bromo-2-Chloro-6-Methyl-Nicotinic Acid
CAS No.	1256809-64-9
Molecular Formula	C7H5BrClNO2
Molecular Weight	250.48 g/mol
Synonyms	5-Bromo-2-chloro-6-methylpyridine-3-carboxylic acid; 2-Chloro-5-bromo-6-methylnicotinic acid; 3-Carboxy-5-bromo-2-chloro-6-methylpyridine; 6-Methyl-5-bromo-2-chloronicotinic acid; 5-Bromo-2-chloro-6-picolinic acid; 2-Chloro-5-bromo-6-picolinic acid; 5-Bromo-2-chloro-6-methyl-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Chloro-6-Methyl-Nicotinic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality commitment supports compliance with relevant guidelines for pharmaceutical intermediates and fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.